Released on: January 23, 2008, 3:14 pm

Press Release Author: Belinda De Leon / Trevigen, Inc.

Industry: Biotech

Press Release Summary: Trevigen announces the release of new polyclonal antibodies
to Collagen I, Laminin I, Fibronectin and Vitronectin.


Press Release Body: Trevigen announces the release of new polyclonal antibodies to
Collagen I, Laminin I, Fibronectin and Vitronectin. These antibodies can be used to
localize Collagen I, Laminin I, Vitronectin and Fibronectin within basement
membranes. They can also be used for Western Blots, Immunocytochemistry,
Immunohistochemistry, and ELISAs.

Collagen, Type I (collagen I), adds structure and strength to connective tissues.
Mutations in the collagen I gene are associated with Ehlers Danlos syndrome,
osteogenesis imperfecta and idiopathic osteoporosis. Trevigen\'s rat collagen I
polyclonal antibodyis reactive in ELISA and can be used for Western blots and
immunofluorescence in frozen and paraffin sections.

Laminin-1 is a major glycoprotein component of extracellular basement membranes,
which induces a variety of cellular responses, including cell attachment.
Immunofluorescence studies have revealed transient and constitutive expression of
these chains, and secretion into the epithelial basement membrane. Trevigen\'s
polyclonal mouse laminin-1 antibody can be used in the localization of laminin-1 in
tissues by immunofluorescence.

Vitronectin is a plasma glycoprotein that circulates in the blood as a mixture of 75
kDa and 65 kDa forms. It is a major cell adhesive glycoprotein and is a common
component of extracellular matrices and plasma. It competes effectively with other
plasma proteins for binding to cells, and is often involved in cell attachment,
regulation of blood coagulation and immune responses. Trevigen\'s Bovine vitronectin
polyclonal antibody can be used in ELISAs, and for localizing vitronectin in frozen
and formalin fixed, paraffin embedded tissues by immunofluorescence.

Fibronectin is an extracellular matrix protein that is found abundantly in blood,
connective tissues, and provisional matrices associated with malignant
transformation of migratory cells, and has demonstrated functions in both cell-cell
and cell-matrix interactions. Trevigen\'s rabbit polyclonal antibody can be used in
ELISAs, and for localizing fibronectin in frozen and formalin fixed paraffin
sections by immunofluorescence.

Trevigen, Inc. develops, manufactures and markets an extensive line of Cultrex®
brand products for the promotion of cell growth, cellular differentiation and for
the study of cancer cell behavior. For details, contact Trevigen, at 800-873-8443,
info@trevigen.com or visit our website at www.trevigen.com.


Web Site: http://www.trevigen.com

Contact Details: Belinda De Leon
Trevigen, Inc.
8405 Helgerman Court
Gaithersburg, MD 20877
info@trevigen.com
1.800.TREVIGEN
TEL: (301)216-2800
FAX: (301)560-4973